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The main focus of the work is the molecular interaction between the protozoan parasite Toxoplasma gondii and the host cell. This facultative intracellular parasite seems alters some physiological features of the host cell (e.g. induction of migration in DC, resistance to Apoptosis). The target is to identify the molecular mechanism by which Toxoplasma influences the host cell.
In vivo biophotonic imaging, 2D-electrophoresis
 | Lambert H., Hitziger N., Dellacasa I., Svensson M., Barragan A. Induction of dendritic cell migration upon Toxoplasma gondii infection potentiates parasite dissemination and requires G protein-coupled signaling. Online publication date: 10-May-2006 doi: 10.1111/j.1462-5822.2006.00735.x Cellular Microbiology
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| Hitziger N., Dellacasa I., Albiger B., Barragan A. Dissemination of Toxoplasma gondii to immunoprivileged organs and role of Toll/Interleukin-1 receptor signaling for host resistance assessed by in vivo bioluminescence imaging. Cellular Microbiology 2005 Jun;7(6):837-48
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Identification of translocated proteins transloacted from Toxoplasma gondii into the infected host cell
Antonio Barragan, Associate Professor (Center for Infectious Medicine)
Members
Junior faculty/post-docs
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