Kristina Broliden (PI), Thomas Tolfvenstam (MD, research assistant), Oscar Norbeck (MD, post-doc), Anna Lindblom (MD, PhD-student), Igge Gustafsson (MD)
Project start and end
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Hepatitis C virus (HCV) is a significant health problem since it often causes life-long persistent infections with chronic hepatitis that may result in cirrhosis and liver cancer. Previous studies
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Human CD1d-restricted natural killer T (NKT) cells represent a subset of lymphocytes with innate characteristics and immunoregulatory functions. We have previously observed that the NKT cell
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The aim of our studies is to better understand how virus-cell interactions and effector molecules within the innate immune system may impact HIV infection. In line with this, we are studying how
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Myelin surrounding nerves is specialized membrane enriched in glycosphingolipids and cholesterol and with a limited number of proteins, compared to a the wide variety of lipids and proteins that are
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The research of my group is focused on the molecular mechanism leading to cell death and immunological impairment during HIV infection. During the last few years we have described that HIV infection
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Background
During the past ten years, it has become clear that not all humans are equally susceptible to infection by HIV-1 and several examples of natural protection have been documented. The most
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